EXTRA: Laborratory Achievement in Vampire Survivors

Rosaries are a random powerup drop that kill all enemies on screen, and they're pretty rare. If you have already gotten this many, the achievement will unlock immediately after ending your first new run with this title update. If you don't have this many Rosaries, I believe the fastest way to grind it out and eliminate any RNG is to play with Sigma on Cappella Magna. There are three Rosaries on this map in a vertical line directly south of where you spawn. Start a run, make a beeline for them, quit the run after you've gotten all three, and then repeat until you unlock this achievement. If you're doing all content before this title update, no grinding should be necessary.